CD80 Rabbit Polyclonal Antibody($99/20μL)

Summary

Production Name	CD80 Rabbit Polyclonal Antibody
Description	Rabbit polyclonal Antibody
Host	Rabbit
Application	IHC,ICC/IF,ELISA
Reactivity	Human,Rat,Mouse

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Polyclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% New type preservative N.
Purification	Affinity purification

Immunogen

Gene Name	CD80
Alternative Names	T-lymphocyte activation antigen CD80 (Activation B7-1 antigen;BB1;CTLA-4 counter-receptor B7.1;B7;CD antigen CD80)
Gene ID	941
SwissProt ID	P33681

Application

Dilution Ratio	IHC 1:50-1:200,ICC/IF 1:50-1:200,ELISA 1:10000-1:20000
Molecular Weight

Background

The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011],function:Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with adenovirus subgroup B fiber proteins and acts as a receptor for these viruses.,tissue specificity:Expressed on activated B-cells, macrophages and dendritic cells.,

Research Area

Cell adhesion molecules (CAMs);Toll_Like;Intestinal immune network for IgA production;Type I diabetes mellitus;Autoimmune thyroid disease;Systemic lupus erythematosus;Allograft rejection;Graft-versus-host disease;Viral myocarditis;