CDC42 Rabbit Monoclonal Antibody

Summary

Production Name	CDC42 Rabbit Monoclonal Antibody
Description	Recombinant rabbit monoclonal antibody
Host	Rabbit
Application	WB
Reactivity	Human,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Purified antibody in TBS with 0.05% sodium azide,0.05%protective protein and 50% glycerol.
Purification	Affinity Purification

Immunogen

Gene Name	CDC42
Alternative Names	CDC42; CDC42Hs; G25K; TKS
Gene ID	998
SwissProt ID	P60953

Application

Dilution Ratio	WB 1:500-1:1000
Molecular Weight	Calculated MW: 21 kDa; Observed MW: 21 kDa

Background

Rac and Cdc42 are members of the Rho-GTPase family. In mammals, Rac exists as three isoforms, Rac1, Rac2 and Rac3, which are highly similar in sequence. Rac1 and Cdc42, the most widely studied of this group, are ubiquitously expressed. Rac and Cdc42 play key signaling roles in cytoskeletal reorganization, membrane trafficking, transcriptional regulation, cell growth and development.

Research Area

MAPK signaling pathway,Hippo signaling pathway