CIRBP Rabbit Monoclonal Antibody

CIRBP Rabbit Monoclonal Antibody

Size1:50μL Price1:$188 $99
Size2:100μL Price2:$338 $180
Application:WB,IHC-P,IP
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:CIRBP SKU: AMRe01829 Category: Rabbit Monoclonal Antibody Tags: , , , , , , ,

Datasheet

Summary

Production Name

CIRBP Rabbit Monoclonal Antibody

Description

Rabbit Monoclonal antibody

Host

Rabbit

Application

WB,IHC-P,IP

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification

Affinity Purification

 

Immunogen

Gene Name

CIRBP

Alternative Names

CIRP

Gene ID

1153

SwissProt ID

Q14011

 

Application

Dilution Ratio

WB: 1:500-1:1000 IHC: 1:50-1:100 IP: 1:20

Molecular Weight

Calculated MW: 19 kDa; Observed MW: 19 kDa

 

Background

Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor . Promotes assembly of stress granules (SGs), when overexpressed.

 

Research Area

Epigenetics and Nuclear Signaling

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