CXCR4 Rabbit Monoclonal Antibody

CXCR4 Rabbit Monoclonal Antibody

Cat: AMRe83746
Size:50μL Price:$168
Size:100μL Price:$300
Application:WB,IHC,ICC/IF,ICC
Reactivity:Human,Mouse
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:CXCR4 Category: Recombinant Monoclonal Antibody Tags:

Summary

Production Name

CXCR4 Rabbit Monoclonal Antibody

Description

Recombinant rabbit monoclonal antibody

Host

Rabbit

Application

WB,IHC,ICC/IF,ICC

Reactivity

Human,Mouse

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% protective protein and 50% glycerol.

Purification

Affinity Purification

 

Immunogen

Gene Name

CXCR4

Alternative Names

CD184 ; CXCR4; C-X-C chemokine receptor type 4; FB22; Fusin; HM89; LCR1; LESTR; NPYRL; SDF-1 receptor; Stromal cell- derived factor 1 receptor;;CXCR4

Gene ID

SwissProt ID

P61073

 

Application

Dilution Ratio

WB 1:500-1:1000,IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200

Molecular Weight

Calculated MW: 40 kDa ; Observed MW: 43 kDa

 

Background

Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ions levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhance intracellular calcium ions and reduce cellular cAMP levels. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Could be involved in cerebellar development.

 

Research Area

Related products

   💬 WhatsApp