Caspase 9 Rabbit Monoclonal antibody

Caspase 9 Rabbit Monoclonal antibody

Size1:50μL Price1:$158 $99
Size2:100μL Price2:$288 $180
Application:WB,IP
Reactivity:Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:Casp9 SKU: AMRe01765 Category: Rabbit Monoclonal Antibody Tags: , , , , , , ,

Datasheet

Summary

Production Name

Caspase 9 Rabbit Monoclonal antibody

Description

Recombinant Rabbit Monoclonal antibody

Host

Rabbit

Application

WB,IP

Reactivity

Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification

Affinity Purified

 

Immunogen

Gene Name

Casp9

Alternative Names

CASP 9; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; APAF-3; ICE-like apoptotic protease 6; ICE-LAP6; Caspase-9 subunit p35; Caspase-9 subunit p10; CASP9; MCH6

Gene ID

12371

SwissProt ID

Q8C3Q9

 

Application

Dilution Ratio

WB: 1:500-1:1000 IP: 1:20

Molecular Weight

Calculated MW: 50 kDa; Observed MW: 50 kDa

 

Background

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).

 

Research Area

Cell Biology

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