Chk2 Rabbit Monoclonal Antibody

Chk2 Rabbit Monoclonal Antibody

Cat: AMRe85432
Size:50μL Price:$168
Size:100μL Price:$300
Application:WB,ICC,IP

Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge).
See other 26 conjugates.

Gene Name:Chk2
Category: Recombinant Monoclonal Antibody Tags: , , , , , ,

Summary

Production Name

Chk2 Rabbit Monoclonal Antibody

Description

Recombinant rabbit monoclonal antibody

Host

Rabbit

Application

WB,ICC,IP

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%protective protein and 50% glycerol.

Purification

Affinity Purification

 

Immunogen

Gene Name

Chk2

Alternative Names

CHEK2; CDS1; CHK2; RAD53; Serine/threonine-protein kinase Chk2; CHK2 checkpoint homolog; Cds1 homolog; Hucds1; hCds1; Checkpoint kinase 2

Gene ID

11200

SwissProt ID

O96017

 

Application

Dilution Ratio

WB 1:500-1:1000,ICC 1:50-1:200,IP 1:10-1:20

Molecular Weight

Calculated MW: 61 kDa; Observed MW: 61 kDa

 

Background

These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function.

 

Research Area

Apoptosis

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