Name: DGCR8 Rabbit Monoclonal Antibody
Brand: Enkilife Limited
SKU: AMRe85504
Price: 168 USD
Availability: InStock

DGCR8 Rabbit Monoclonal Antibody

Cat: AMRe85504

Size:20μL Price:$98
Size:50μL Price:$168
Size:100μL Price:$300
Application:WB,ICC,IP
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:DGCR8 Category: Recombinant Monoclonal Antibody Tags: Rabbit, Unconjugated, WB, IP, ICC, Human, Mouse, Rat

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Summary

Production Name	DGCR8 Rabbit Monoclonal Antibody
Description	Recombinant rabbit monoclonal antibody
Host	Rabbit
Application	WB,ICC,IP
Reactivity	Human,Mouse,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Purified antibody in TBS with 0.05% sodium azide,0.05%protective protein and 50% glycerol.
Purification	Affinity Purification

Immunogen

Gene Name	DGCR8
Alternative Names	DGCR8; DGCRK6; Gy1; C22orf12; D16Wis2; pasha
Gene ID	54487
SwissProt ID	Q8WYQ5

Application

Dilution Ratio	WB 1:500-1:1000,ICC 1:50-1:200,IP 1:10-1:20
Molecular Weight	Calculated MW: 86 kDa; Observed MW: 120 kDa

Background

Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs DROSHA to cleave 11 bp away form the junction to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs.

Research Area