Estrogen Receptor alpha Rabbit Monoclonal antibody

Estrogen Receptor alpha Rabbit Monoclonal antibody

SKU: AMRe01960 ★ ★ ★ ★ ★
Size1:50μL Price1:$188 $99
Size2:100μL Price2:$338 $180
Application:WB,IHC-F,IHC-P,ICC/IF,IP,ChIP
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:ESR1 Category: Recombinant Monoclonal Antibody Tags: , , , , , , , , ,

Summary

Production Name

Estrogen Receptor alpha Rabbit Monoclonal antibody

Description

Recombinant Rabbit Monoclonal antibody

Host

Rabbit

Application

WB,IHC-F,IHC-P,ICC/IF,IP,ChIP

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification

Affinity Purified

 

Immunogen

Gene Name

ESR1

Alternative Names

ESR1; Era; Eralpha; Estrogen receptor; Estradiol receptor; ER-alpha; Estrogen receptor 1; NR3A1; ER; ESR; ESRA; Estrogen receptor alpha

Gene ID

2099

SwissProt ID

P03372

 

Application

Dilution Ratio

WB: 1:500-1:1000 IHC: 1:50-1:100 IF: 1:50-1:200 IP: 1:20 ChIP: 1:20

Molecular Weight

Calculated MW: 66 kDa; Observed MW: 66 kDa

 

Background

ER (estrogen receptor 1) a member of the steroid receptor superfamily, contains highly conserved DNA binding (DBD) and ligand binding domains (LBD). Through its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2, respectively), ER regulates transcription by recruiting coactivator proteins and interacting with general transcriptional machinery. Phosphorylation provides an important mechanism to regulate ER activity. ER is phosphorylated on multiple sites.

 

Research Area

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