FADD Rabbit Polyclonal Antibody($99/20μL)

FADD Rabbit Polyclonal Antibody($99/20μL)

Cat: APRab00259
Size:20μL Price:$99
Size:50μL Price:$150
Size:100μL Price:$280

Size:200μL Price:$520
Application:WB,IHC,FC

Reactivity:Mouse
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge).
See other 26 conjugates.

Gene Name:Fadd Category: Polyclonal Antibody Tags: , , , , , ,

Summary

Production Name

FADD Rabbit Polyclonal Antibody

Description

Rabbit polyclonal Antibody

Host

Rabbit

Application

WB,IHC,FC

Reactivity

Mouse

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification

Affinity Chromatography

 

Immunogen

Gene Name

Fadd

Alternative Names

FADD protein; GIG3; Growth inhibiting gene 3 protein; Mediator of receptor induced toxicity; MORT1

Gene ID

14082

SwissProt ID

Q61160

 

Application

Dilution Ratio

WB 1:500-1:1000,IHC 1:50-1:100,FC 1:50-1:100

Molecular Weight

Calculated MW: 23 kDa; Observed MW: 28 kDa

 

Background

Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.

 

Research Area

Cell Biology

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