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Furin (6Z15) Rabbit Monoclonal Antibody

Furin (6Z15) Rabbit Monoclonal Antibody

Cat: AMRe11184
Size:50μL Price:$128
Size:100μL Price:$230
Size:200μL Price:$380
Application:WB,IHC,ICC/IF
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:FURIN Category: Recombinant Monoclonal Antibody Tags:

Summary

Production Name

Furin (6Z15) Rabbit Monoclonal Antibody

Description

Recombinant rabbit monoclonal antibody

Host

Rabbit

Application

WB,IHC,ICC/IF

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Purification

Affinity purification

 

Immunogen

Gene Name

FURIN

Alternative Names

FUR; FURIN; PACE; PCSK3; SPC1;

Gene ID

5045

SwissProt ID

P09958

 

Application

Dilution Ratio

WB 1:1000-1:5000,IHC 1:50-1:100,ICC/IF 1:100-1:200

Molecular Weight

87kDa

 

Background

Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif. Ubiquitous endoprotease within constitutive secretory pathways capable of cleavage at the RX(K/R)R consensus motif (PubMed:11799113, PubMed:1629222, PubMed:1713771, PubMed:2251280, PubMed:24666235, PubMed:25974265, PubMed:7592877, PubMed:7690548, PubMed:9130696). Mediates processing of TGFB1, an essential step in TGF-beta-1 activation (PubMed:7737999). Converts through proteolytic cleavage the non-functional Brain natriuretic factor prohormone into its active hormone BNP(1-32) (PubMed:20489134, PubMed:21763278).

 

Research Area

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