Summary
Performance
Immunogen
Application
Background
PRLHR is a 7-transmembrane domain receptor for prolactin-releasing hormone (PRLH; MIM 602663) that is highly expressed in anterior pituitary (Ozawa et al., 2002 [PubMed 11923475]).[supplied by OMIM, Mar 2008],function:Receptor for prolactin-releasing peptide (PrRP). Implicated in lactation, regulation of food intake and pain-signal processing.,induction:Repressed by bromocriptine, a dopamine agonist.,similarity:Belongs to the G-protein coupled receptor 1 family.,subunit:Interacts through its C-terminal region with the PDZ domain-containing proteins GRIP1, GRIP2 and PICK1. Interacts with PDZ domains 4 and 5 of GRIP1 and with the PDZ domain of PICK1.,tissue specificity:Only detected in the pituitary gland and in all cell types of pituitary adenomas.,
Research Area
Neuroactive ligand-receptor interaction;
