HDAC11 Rabbit Monoclonal Antibody

Summary

Production Name	HDAC11 Rabbit Monoclonal Antibody
Description	Recombinant rabbit monoclonal antibody
Host	Rabbit
Application	WB,IP
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification	Affinity Purification

Immunogen

Gene Name	HDAC11
Alternative Names	HDAC11; HD11; Histone deacetylase 11
Gene ID	79885
SwissProt ID	Q96DB2

Application

Dilution Ratio	WB 1:500-1:1000,IP 1:20-1:50
Molecular Weight	Calculated MW: 39 kDa; Observed MW: 39 kDa

Background

play an important role in the modification of chromatin structure and thus in the suppression and activation of transcription and cellular differentiation. There are 11 members in the HDAC family that are classified into four classes. Class I HDACs represent homologs of the yeast histone deacetylase RPD3, class II HDACs share strong homology with the yeast histone deacetylase HDA1, class III HDAC are closely related to the yeast SIR2 protein, and class IV HDACs comprises Histone deacetylase 11 (HDAC11)-related enzymes. HDAC11 contains 347 amino acid residues.

Research Area

Epigenetics and Nuclear Signaling