Summary
Performance
Immunogen
Application
Background
This gene encodes a mitochondrial 3-hydroxyisobutyrate dehydrogenase enzyme. The encoded protein plays a critical role in the catabolism of L-valine by catalyzing the oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde. [provided by RefSeq, Nov 2011],catalytic activity:3-hydroxy-2-methylpropanoate + NAD(+) = 2-methyl-3-oxopropanoate + NADH.,similarity:Belongs to the 3-hydroxyisobutyrate dehydrogenase family.,subunit:Homodimer.,
Research Area
Valine; leucine and isoleucine degradation;
