Name: HIF Prolyl Hydroxylases Rabbit Monoclonal Antibody
Brand: Enkilife Limited
SKU: AMRe84748
Price: 168 USD
Availability: InStock
Rating: 5 (1 reviews)

HIF Prolyl Hydroxylases Rabbit Monoclonal Antibody

Cat: AMRe84748

Size:50μL Price:$168
Size:100μL Price:$300
Application:WB,IHC,FC,IP
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:HIF Prolyl Hydroxylases Category: Recombinant Monoclonal Antibody Tags: Rabbit, Unconjugated, WB, IP, IHC, FC, Human

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Summary

Production Name	HIF Prolyl Hydroxylases Rabbit Monoclonal Antibody
Description	Recombinant rabbit monoclonal antibody
Host	Rabbit
Application	WB,IHC,FC,IP
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Purified antibody in PBS with 0.05% sodium azide,0.05% protective protein and 50% glycerol.
Purification	Affinity Purification

Immunogen

Gene Name	HIF Prolyl Hydroxylases
Alternative Names	EGLN4 ; HIFPH4; Hypoxia inducible factor prolyl 4 hydroxylase; P4H with transmembrane domain; P4htm; PH4; PHD4; Proline 4 hydroxylase; Prolyl hydroxlase domain containing 4;;HIF PH4
Gene ID
SwissProt ID	Q9NXG6

Application

Dilution Ratio	WB 1:1000-1:2000,IHC 1:100-1:200,FC 1:20-1:100,IP 1:20-1:50
Molecular Weight	Calculated MW: 57 kDa ; Observed MW: 47 kDa

Background

Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.

Research Area