Name: IDH1 Rabbit Monoclonal Antibody
Brand: Enkilife Limited
SKU: AMRe01425
Price: 158 USD
Availability: InStock
Rating: 5 (1 reviews)

IDH1 Rabbit Monoclonal Antibody

Cat: AMRe01425

Size:50μL Price:$158
Size:100μL Price:$288
Size:200μL Price:$520
Application:WB,IHC,IP
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:IDH1 Category: Recombinant Monoclonal Antibody Tags: Unconjugated, Signal Transduction, Rabbit, WB, IHC, IP, Human, Mouse, Rat

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Summary

Production Name	IDH1 Rabbit Monoclonal Antibody
Description	Recombinant rabbit monoclonal antibody
Host	Rabbit
Application	WB,IHC,IP
Reactivity	Human,Mouse,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification	Affinity Purification

Immunogen

Gene Name	IDH1
Alternative Names	IDH1; PICD; Isocitrate dehydrogenase [NADP] cytoplasmic; IDH; Cytosolic NADP-isocitrate dehydrogenase; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase
Gene ID	3417
SwissProt ID	O75874

Application

Dilution Ratio	WB 1:500-1:1000,IHC 1:50-1:100,IP 1:20-1:50
Molecular Weight	Calculated MW: 47 kDa; Observed MW: 47 kDa

Background

Genetic variations are associated with cartilaginous tumors such as enchondroma or chondrosarcoma. Mutations of Arg-132 to Cys, Gly or His abolish the conversion of isocitrate to alpha-ketoglutarate. Instead, alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate.

Research Area

Signal Transduction