Summary
Performance
Immunogen
Application
Background
This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Use of the recombinant form of this protein has been shown to be effective in reducing the symptoms and duration of the common cold. [provided by RefSeq, Jun 2011],function:Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.,pharmaceutical:Available under the names Roferon-A (Roche) or Intron-A (Schering-Plough). Used as an anticancer drug for its antiproliferative activity.,polymorphism:Three forms exist; alpha-2a (shown here), alpha-2b and alpha-2c.,similarity:Belongs to the alpha/beta interferon family.,
Research Area
Cytokine-cytokine receptor interaction;Regulation of autophagy;Antigen processing and presentation;Toll_Like;RIG-I-like receptor;Cytosolic DNA-sensing pathway;Jak_STAT;Natural killer cell mediated cytotoxicity;Autoimmune thyroid disease;
