Summary
Performance
Immunogen
Application
Background
The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies. Alternative splicing results in multiple splice variants. [provided by RefSeq, Dec 2015],function:Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1.,online information:Interleukin-17 entry,similarity:Belongs to the IL-17 family.,tissue specificity:Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.,
Research Area
Cytokine-cytokine receptor interaction;
