Name: Integrin beta 3 (3C12) Mouse Monoclonal Antibody
Brand: Enkilife Limited
SKU: AMM03440
Price: 150 USD
Availability: InStock
Rating: 5 (1 reviews)

Integrin beta 3 (3C12) Mouse Monoclonal Antibody

Cat: AMM03440

Size:50μL Price:$150
Size:100μL Price:$280
Size:200μL Price:$520
Application:WB
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:ITGB3 Category: Mouse Monoclonal Antibody Tags: Unconjugated, Tags & Cell Markers, Mouse, WB, Human

Datasheet

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Summary

Production Name	Integrin beta 3 (3C12) Mouse Monoclonal Antibody
Description	Mouse monoclonal Antibody
Host	Mouse
Application	WB
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG1
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% sodium azide, pH 7.3.
Purification	Affinity Purification

Immunogen

Gene Name	ITGB3
Alternative Names	ITGB3; GP3A; Integrin beta-3; Platelet membrane glycoprotein IIIa; GPIIIa; CD antigen CD61
Gene ID	3690
SwissProt ID	P05106

Application

Dilution Ratio	WB 1:500-1:1000
Molecular Weight	Calculated MW: 87 kDa; Observed MW: 110 kDa

Background

Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. Fibrinogen binding enhances SELP expression in activated platelets (By similarity).

Research Area

Tags & Cell Markers