Summary
| Production Name | KD-Validated BCLAF1 Recombinant Rabbit Monoclonal Antibody |
| Description | KD-Validated antibody |
| Host | Rabbit |
| Application | WB,FCM,ICC,IHC-P |
| Reactivity | Human,Mouse,Rat |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | Rabbit IgG |
| Clonality | Rabbit mAb |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide. |
| Purification | Affinity purification |
Immunogen
| Gene Name | BCLAF1 |
| Alternative Names | BCLAF1; BCL2 Associated Transcription Factor 1; BTF; BCLAF1 And THRAP3 Family Member 1; KIAA0164; Bcl-2-Associated Transcription Factor 1; BCL2-Associated Transcription Factor 1; BK211L9.1; Btf |
| Gene ID | 9774 |
| SwissProt ID | Q9NYF8 |
Application
| Dilution Ratio | WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000; IHC-P 1:100-1:200 |
| Molecular Weight | Calculated MW: 106.1kDa |
Background
This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Research Area
Cell Biology,Epigenetics and Nuclear Signaling