KD-Validated Bcl-2 Recombinant Rabbit Monoclonal Antibody-EnkiLife

KD-Validated Bcl-2 Recombinant Rabbit Monoclonal Antibody

Summary

Production Name	KD-Validated Bcl-2 Recombinant Rabbit Monoclonal Antibody
Description	KD-Validated antibody
Host	Rabbit
Application	WB,FCM,IHC-P
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	Rabbit IgG
Clonality	Rabbit mAb
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Purification	Affinity purification

Immunogen

Gene Name	BCL2
Alternative Names	BCL2 Apoptosis Regulator; PPP1R50; Bcl-2; Protein Phosphatase 1, Regulatory Subunit 50; Apoptosis Regulator Bcl-2; B-Cell CLL/Lymphoma 2; BCL2, Apoptosis Regulator
Gene ID	596
SwissProt ID	P10415

Application

Dilution Ratio	WB 1:1,000-1:5,000; FC 1:200-1:2,000; IHC-P 1:100-1:200
Molecular Weight	Calculated MW: 26.3kDa

Background

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

Research Area

Cell Biology,Signal Transduction,Cancer,Kits/ Lysates/ Other,Metabolism