Name: KD-Validated Checkpoint Kinase 1 Recombinant Rabbit Monoclonal Antibody
Brand: Enkilife Limited
SKU: KVAb01442
Price: 118 USD
Availability: InStock

WesternBlot(WB) - KD-Validated Checkpoint Kinase 1 Recombinant Rabbit Monoclonal Antibody KVAb01442

Immunocytochemistry(ICC) - KD-Validated Checkpoint Kinase 1 Recombinant Rabbit Monoclonal Antibody KVAb01442

KD-Validated Checkpoint Kinase 1 Recombinant Rabbit Monoclonal Antibody

Size:20μL Price:$118
Size:50μL Price:$218
Size:100μL Price:$318
Application:WB,FCM,ICC
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Gene Name:CHEK1

SKU: KVAb01442

Detail

Summary

Production Name	KD-Validated Checkpoint Kinase 1 Recombinant Rabbit Monoclonal Antibody
Description	KD-Validated antibody
Host	Rabbit
Application	WB,FCM,ICC
Reactivity	Human,Mouse,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	Rabbit IgG
Clonality	Rabbit mAb
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Purification	Affinity purification

Immunogen

Gene Name	CHEK1
Alternative Names	CHEK1; Checkpoint Kinase 1; CHK1; Serine/Threonine-Protein Kinase Chk1; Cell Cycle Checkpoint Kinase; CHK1 Checkpoint Homolog; EC 2.7.11.1; Checkpoint, S. Pombe, Homolog Of, 1; CHK1 (Checkpoint, S.Pombe) Homolog; CHK1 Checkpoint Homolog (S. Pombe); Checkpoint Kinase-1; EC 2.7.11; OZEMA21; Chk1-S
Gene ID	1111
SwissProt ID	O14757

Application

Dilution Ratio	WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000
Molecular Weight	Calculated MW: 54.4kDa

Background

The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011]

Research Area

Epigenetics and Nuclear Signaling,Cancer