KD-Validated Cytoplasmic Fmr1 Interacting Protein 1 Recombinant Rabbit Monoclonal Antibody
Size:20μL Price:$118
Size:50μL Price:$218
Size:100μL Price:$318
Application:WB,FCM,ICC

Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Gene Name:CYFIP1
SKU: KVAb01117
Detail

Summary

Production Name

KD-Validated Cytoplasmic Fmr1 Interacting Protein 1 Recombinant Rabbit Monoclonal Antibody

Description

KD-Validated antibody

Host

Rabbit

Application

WB,FCM,ICC

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

Rabbit IgG

Clonality

Rabbit mAb

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Purification

Affinity purification

 

Immunogen

Gene Name

CYFIP1

Alternative Names

CYFIP1; Cytoplasmic FMR1 Interacting Protein 1; P140SRA-1; KIAA; Cytoplasmic FMRP Interacting Protein 1; Cytoplasmic FMR1-Interacting Protein 1; Specifically Rac1-Associated Protein 1; Selective Hybridizing Clone; P140sra-1; SRA-1; Sra-1; SRA1

Gene ID

23191

SwissProt ID

Q7L576

 

Application

Dilution Ratio

WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000

Molecular Weight

Calculated MW: 145.2kDa

 

Background

This gene encodes a protein that regulates cytoskeletal dynamics and protein translation. The encoded protein is a component of the WAVE regulatory complex (WRC), which promotes actin polymerization. This protein also interacts with the synaptic functional regulator FMR1 protein and translation initiation factor 4E to inhibit protein translation. A large chromosomal deletion including this gene is associated with increased risk of schizophrenia and epilepsy in human patients. Reduced expression of this gene has been observed in various human cancers and the encoded protein may inhibit tumor invasion. [provided by RefSeq, Mar 2022]

 

Research Area

Cancer

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