Name: KD-Validated Dyskerin Pseudouridine Synthase 1 Recombinant Rabbit Monoclonal Antibody
Brand: Enkilife Limited
SKU: KVAb00009
Price: 118 USD
Availability: InStock

WesternBlot(WB) - KD-Validated Dyskerin Pseudouridine Synthase 1 Recombinant Rabbit Monoclonal Antibody KVAb00009

Flow cytometry - KD-Validated Dyskerin Pseudouridine Synthase 1 Recombinant Rabbit Monoclonal Antibody - KVAb00009

KD-Validated Dyskerin Pseudouridine Synthase 1 Recombinant Rabbit Monoclonal Antibody

Size:20μL Price:$118
Size:50μL Price:$218
Size:100μL Price:$318
Application:WB,FCM
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Gene Name:DKC1

SKU: KVAb00009

Detail

Summary

Production Name	KD-Validated Dyskerin Pseudouridine Synthase 1 Recombinant Rabbit Monoclonal Antibody
Description	KD-Validated antibody
Host	Rabbit
Application	WB,FCM
Reactivity	Human,Mouse,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	Rabbit IgG
Clonality	Rabbit mAb
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Purification	Affinity purification

Immunogen

Gene Name	DKC1
Alternative Names	DKC1; Dyskerin Pseudouridine Synthase 1; NOLA4; XAP101; NAP57; H/ACA Ribonucleoprotein Complex Subunit DKC1; H/ACA Ribonucleoprotein Complex Subunit; Nopp140-Associated Protein Of 57 KDa; Nucleolar Protein Family A Member 4; Dyskeratosis Congenita 1, Dyskerin; Nucleolar Protein NAP57; SnoRNP Protein DKC1; CBF5 Homolog; Dyskerin; CBF5; DKC; EC 5.4.99.-; EC 5.4.99; DYSKERIN; CHINE1; Cbf5; DKCX
Gene ID	1736
SwissProt ID	O60832

Application

Dilution Ratio	WB 1:1,000-1:5,000; FC 1:200-1:2,000
Molecular Weight	Calculated MW: 57.7kDa

Background

This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Research Area

Epigenetics and Nuclear Signaling