Summary
| Production Name | KD-Validated FDFT1 Mouse Monoclonal Antibody |
| Description | KD-Validated antibody |
| Host | Mouse |
| Application | WB,FCM |
| Reactivity | Human |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | Mouse IgG2a |
| Clonality | Mouse mAb |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide. |
| Purification | Affinity purification |
Immunogen
| Gene Name | FDFT1 |
| Alternative Names | FDFT1; Farnesyl-Diphosphate Farnesyltransferase 1; SQS; Squalene Synthase; FPP:FPP Farnesyltransferase; EC 2.5.1.21; SS; Farnesyl-Diphosphate Farnesyltransferase; Presqualene-Di-Diphosphate Synthase; Squalene Synthetase; DGPT; ERG9; SQSD |
| Gene ID | 2222 |
| SwissProt ID | P37268 |
Application
| Dilution Ratio | WB 1:400-1:2,000; FC 1:200-1:2,000 |
| Molecular Weight | Calculated MW: 48.1kDa |
Background
This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008]
Research Area
Cardiovascular,Neuroscience,Cancer,Metabolism