Name: KD-Validated HDAC4 Recombinant Rabbit Monoclonal Antibody
Brand: Enkilife Limited
SKU: KVAb00754
Price: 118 USD
Availability: InStock

WesternBlot(WB) - KD-Validated HDAC4 Recombinant Rabbit Monoclonal Antibody KVAb00754

Immunocytochemistry(ICC) - KD-Validated HDAC4 Recombinant Rabbit Monoclonal Antibody KVAb00754

KD-Validated HDAC4 Recombinant Rabbit Monoclonal Antibody

Size:20μL Price:$118
Size:50μL Price:$218
Size:100μL Price:$318
Application:WB,FCM,ICC
Reactivity:Human
Conjugate:Unconjugated
Gene Name:HDAC4

SKU: KVAb00754

Detail

Summary

Production Name	KD-Validated HDAC4 Recombinant Rabbit Monoclonal Antibody
Description	KD-Validated antibody
Host	Rabbit
Application	WB,FCM,ICC
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	Rabbit IgG
Clonality	Rabbit mAb
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Purification	Affinity purification

Immunogen

Gene Name	HDAC4
Alternative Names	Histone Deacetylase 4; HD4; KIAA0288; HDAC-A; HA6116; HDAC-4; HDACA; EC 3.5.1.98; BDMR; Brachydactyly-Mental Retardation Syndrome; Histone Deacetylase A; NEDCHID; NEDCHF; AHO3
Gene ID	9759
SwissProt ID	P56524

Application

Dilution Ratio	WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000
Molecular Weight	Calculated MW: 119.0kDa

Background

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]

Research Area

Epigenetics and Nuclear Signaling,Stem Cells,Cardiovascular,Neuroscience