Name: KD-Validated Lamin A/C Recombinant Rabbit Monoclonal Antibody
Brand: Enkilife Limited
SKU: KVAb01348
Price: 118 USD
Availability: InStock

WesternBlot(WB) - KD-Validated Lamin A/C Recombinant Rabbit Monoclonal Antibody KVAb01348

Immunocytochemistry(ICC) - KD-Validated Lamin A/C Recombinant Rabbit Monoclonal Antibody KVAb01348

KD-Validated Lamin A/C Recombinant Rabbit Monoclonal Antibody

Size:20μL Price:$118
Size:50μL Price:$218
Size:100μL Price:$318
Application:WB,FCM,ICC
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Gene Name:LMNA

SKU: KVAb01348

Detail

Summary

Production Name	KD-Validated Lamin A/C Recombinant Rabbit Monoclonal Antibody
Description	KD-Validated antibody
Host	Rabbit
Application	WB,FCM,ICC
Reactivity	Human,Mouse,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	Rabbit IgG
Clonality	Rabbit mAb
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Purification	Affinity purification

Immunogen

Gene Name	LMNA
Alternative Names	LMNA; Lamin A/C; HGPS; MADA; LMN1; Mandibuloacral Dysplasia Type A; Lamin A/C-Like 1; Prelamin-A/C; Progerin; LGMD1B; CMD1A; LMNL1; PRO1; Limb Girdle Muscular Dystrophy 1B (Autosomal Dominant); Cardiomyopathy, Dilated 1A (Autosomal Dominant); Epididymis Secretory Sperm Binding Protein; Progeria 1 (Hutchinson-Gilford Type); Renal Carcinoma Antigen NY-REN-32; 70 KDa Lamin; Lamin C; CMT2B1; CDCD1; FPLD2; Lamin; CDDC; EMD2; FPLD; LDP1; LMNC; FPL; IDC; LFP
Gene ID	4000
SwissProt ID	P02545

Application

Dilution Ratio	WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000
Molecular Weight	Calculated MW: 74.1kDa

Background

The protein encoded by this gene is part of the nuclear lamina, a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, May 2022]

Research Area

Tags & Cell Markers,Signal Transduction