Name: KD-Validated MYC Mouse Monoclonal Antibody
Brand: Enkilife Limited
SKU: KVAb01452
Price: 118 USD
Availability: InStock

WesternBlot(WB) - KD-Validated MYC Mouse Monoclonal Antibody KVAb01452

Immunocytochemistry(ICC) - KD-Validated MYC Mouse Monoclonal Antibody KVAb01452

KD-Validated MYC Mouse Monoclonal Antibody

Size:20μL Price:$118
Size:50μL Price:$218
Size:100μL Price:$318
Application:WB,FCM,ICC
Reactivity:Human
Conjugate:Unconjugated
Gene Name:MYC

SKU: KVAb01452

Detail

Summary

Production Name	KD-Validated MYC Mouse Monoclonal Antibody
Description	KD-Validated antibody
Host	Mouse
Application	WB,FCM,ICC
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	Mouse IgG1 kappa
Clonality	Mouse mAb
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Purification	Affinity purification

Immunogen

Gene Name	MYC
Alternative Names	MYC; MYC Proto-Oncogene, BHLH Transcription Factor; BHLHe39; C-Myc; MYCC; V-Myc Avian Myelocytomatosis Viral Oncogene Homolog; Class E Basic Helix-Loop-Helix Protein 39; Myc Proto-Oncogene Protein; Transcription Factor P64; Proto-Oncogene C-Myc; Myc-Related Translation/Localization Regulatory Factor; Avian Myelocytomatosis Viral Oncogene Homolog; V-Myc Myelocytomatosis Viral Oncogene Homolog; BHLHE39; MRTL
Gene ID	4609
SwissProt ID	P01106

Application

Dilution Ratio	WB 1:400-1:2,000; FC 1:200-1:2,000; ICC 1:100-1:1,000
Molecular Weight	Calculated MW: 48.8kDa

Background

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]

Research Area

Epigenetics and Nuclear Signaling,Stem Cells,Cancer,Signal Transduction