Name: KD-Validated Optineurin Recombinant Rabbit Monoclonal Antibody
Brand: Enkilife Limited
SKU: KVAb00307
Price: 118 USD
Availability: InStock

WesternBlot(WB) - KD-Validated Optineurin Recombinant Rabbit Monoclonal Antibody KVAb00307

Immunocytochemistry(ICC) - KD-Validated Optineurin Recombinant Rabbit Monoclonal Antibody KVAb00307

KD-Validated Optineurin Recombinant Rabbit Monoclonal Antibody

Size:20μL Price:$118
Size:50μL Price:$218
Size:100μL Price:$318
Application:WB,FCM,ICC
Reactivity:Human
Conjugate:Unconjugated
Gene Name:OPTN

SKU: KVAb00307

Detail

Summary

Production Name	KD-Validated Optineurin Recombinant Rabbit Monoclonal Antibody
Description	KD-Validated antibody
Host	Rabbit
Application	WB,FCM,ICC
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	Rabbit IgG
Clonality	Rabbit mAb
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Purification	Affinity purification

Immunogen

Gene Name	OPTN
Alternative Names	OPTN; Optineurin; FIP-2; FIP2; HYPL; HIP7; NRP; TFIIIA-INTP; GLC1E; Transcription Factor IIIA-Interacting Protein; Optic Neuropathy-Inducing Protein; Huntingtin-Interacting Protein 7; Huntingtin-Interacting Protein L; E3-14.7K-Interacting Protein; Huntingtin Yeast Partner L; HIP-7; Tumor Necrosis Factor Alpha-Inducible Cellular Protein Containing Leucine Zipper Domains; Transcrption Factor IIIA-Interacting Protein; Glaucoma 1, Open Angle, E (Adult-Onset); Huntingtin Interacting Protein L; Nemo-Related Protein; NEMO-Related Protein; TFIIIA-IntP; ALS12
Gene ID	10133
SwissProt ID	Q96CV9

Application

Dilution Ratio	WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000
Molecular Weight	Calculated MW: 65.9kDa

Background

This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

Research Area

Immunology,Signal Transduction,Neuroscience