KD-Validated PCAF Recombinant Rabbit Monoclonal Antibody

Summary

Production Name	KD-Validated PCAF Recombinant Rabbit Monoclonal Antibody
Description	KD-Validated antibody
Host	Rabbit
Application	WB,FCM,ICC
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	Rabbit IgG
Clonality	Rabbit mAb
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Purification	Affinity purification

Immunogen

Gene Name	KAT2B
Alternative Names	Lysine Acetyltransferase 2B; P/CAF; P300/CBP-Associated Factor; PCAF; Spermidine Acetyltransferase KAT2B; Histone Acetyltransferase KAT2B; K(Lysine) Acetyltransferase 2B; Histone Acetyltransferase PCAF; Histone Acetylase PCAF; EC 2.3.1.48; GCN5L; GCN5; CREBBP-Associated Factor; EC 2.3.1.57; CAF
Gene ID	8850
SwissProt ID	Q92831

Application

Dilution Ratio	WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000
Molecular Weight	Calculated MW: 93.0kDa

Background

CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq, Jul 2008]

Research Area

Cell Biology,Epigenetics and Nuclear Signaling,Microbiology

KD-Validated PCAF Recombinant Rabbit Monoclonal Antibody

KD-Validated PCAF Recombinant Rabbit Monoclonal Antibody

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