KD-Validated Sp1 Transcription Factor Mouse Monoclonal Antibody-EnkiLife

KD-Validated Sp1 Transcription Factor Mouse Monoclonal Antibody

Summary

Production Name	KD-Validated Sp1 Transcription Factor Mouse Monoclonal Antibody
Description	KD-Validated antibody
Host	Mouse
Application	WB,FCM,ICC
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	Mouse IgG1 kappa
Clonality	Mouse mAb
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Purification	Affinity purification

Immunogen

Gene Name	SP1
Alternative Names	SP1; Sp1 Transcription Factor; Transcription Factor Sp1; Specificity Protein 1; TSFP1
Gene ID	6667
SwissProt ID	P08047

Application

Dilution Ratio	WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000
Molecular Weight	Calculated MW: 80.7kDa

Background

The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]

Research Area

Epigenetics and Nuclear Signaling,Stem Cells,Metabolism