Name: KO-Validated EIF2AK2 Recombinant Rabbit Monoclonal Antibody
Brand: Enkilife Limited
SKU: KVAb00086
Price: 118 USD
Availability: InStock

WesternBlot(WB) - KO-Validated EIF2AK2 Recombinant Rabbit Monoclonal Antibody KVAb00086

Immunocytochemistry(ICC) - KO-Validated EIF2AK2 Recombinant Rabbit Monoclonal Antibody KVAb00086

KO-Validated EIF2AK2 Recombinant Rabbit Monoclonal Antibody

Size:20μL Price:$118
Size:50μL Price:$218
Size:100μL Price:$318
Application:WB,FCM,ICC
Reactivity:Human
Conjugate:Unconjugated
Gene Name:EIF2AK2

SKU: KVAb00086

Detail

Summary

Production Name	KO-Validated EIF2AK2 Recombinant Rabbit Monoclonal Antibody
Description	KD-Validated antibody
Host	Rabbit
Application	WB,FCM,ICC
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	Rabbit IgG
Clonality	Rabbit mAb
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Purification	Affinity purification

Immunogen

Gene Name	EIF2AK2
Alternative Names	EIF2AK2; Eukaryotic Translation Initiation Factor 2 Alpha Kinase 2; PKR; Protein Kinase R; PPP1R83; PRKR; Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent; Interferon-Induced, Double-Stranded RNA-Activated Protein Kinase; Protein Phosphatase 1, Regulatory Subunit 83; Tyrosine-Protein Kinase EIF2AK2; Protein Kinase RNA-Activated; Protein Kinase RNA-Regulated; P1/EIF-2A Protein Kinase; EIF-2A Protein Kinase 2; P68 Kinase; Eukaryotic Translation Initiation Factor 2-Alpha Kinase 2; Interferon-Inducible RNA-Dependent Protein Kinase; Double Stranded RNA Activated Protein Kinase; Interferon-Inducible ElF2alpha Kinase; EC 2.7.11.1; EC 2.7.10.2; EIF2AK1; LEUDEN; DYT33
Gene ID	5610
SwissProt ID	P19525

Application

Dilution Ratio	WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000
Molecular Weight	Calculated MW: 62.1kDa

Background

The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. The encoded protein plays an important role in the innate immune response against multiple DNA and RNA viruses. [provided by RefSeq, Jul 2021]

Research Area

Signal Transduction