KO-Validated ETS Transcription Factor ELK1 Recombinant Rabbit Monoclonal Antibody-EnkiLife

KO-Validated ETS Transcription Factor ELK1 Recombinant Rabbit Monoclonal Antibody

Summary

Production Name	KO-Validated ETS Transcription Factor ELK1 Recombinant Rabbit Monoclonal Antibody
Description	KD-Validated antibody
Host	Rabbit
Application	WB,FCM,ICC
Reactivity	Human,Mouse,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	Rabbit IgG
Clonality	Rabbit mAb
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Purification	Affinity purification

Immunogen

Gene Name	ELK1
Alternative Names	ELK1; ETS Transcription Factor ELK1; ELK1, Member Of ETS Oncogene Family; ETS Domain-Containing Protein Elk-1; Tyrosine Kinase (ELK1) Oncogene; ELK1, ETS Transcription Factor; ETS-Like Gene 1
Gene ID	2002
SwissProt ID	P19419

Application

Dilution Ratio	WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000
Molecular Weight	Calculated MW: 44.9kDa

Background

This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. [provided by RefSeq, Mar 2012]

Research Area

Signal Transduction,Epigenetics and Nuclear Signaling,Cancer