KO-Validated Endonuclease G Recombinant Rabbit Monoclonal Antibody-EnkiLife

KO-Validated Endonuclease G Recombinant Rabbit Monoclonal Antibody

Summary

Production Name	KO-Validated Endonuclease G Recombinant Rabbit Monoclonal Antibody
Description	KD-Validated antibody
Host	Rabbit
Application	WB,FCM,ICC
Reactivity	Human,Mouse,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	Rabbit IgG
Clonality	Rabbit mAb
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Purification	Affinity purification

Immunogen

Gene Name	ENDOG
Alternative Names	ENDOG; Endonuclease G; Endonuclease G, Mitochondrial; Endo G; Mitochondrial Endonuclease G; EC 3.1.30.-
Gene ID	2021
SwissProt ID	Q14249

Application

Dilution Ratio	WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000
Molecular Weight	Calculated MW: 32.6kDa

Background

The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA. [provided by RefSeq, Jul 2008]

Research Area

Cell Biology,Epigenetics and Nuclear Signaling,Cancer,Metabolism