KO-Validated FTO Recombinant Rabbit Monoclonal Antibody-EnkiLife

KO-Validated FTO Recombinant Rabbit Monoclonal Antibody

Cat: KVAb00114

Size:20μL Price:$118
Size:50μL Price:$218
Size:100μL Price:$318
Application:WB,FCM,ICC
Reactivity:Human,Rat
Conjugate:Unconjugated
Gene Name:FTO Category: KO&KD Validated Antibodies Tags: WB, FCM, ICC, Human, Rat, Rabbit, Unconjugated, Neuroscience, Cardiovascular, Metabolism

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Summary

Production Name	KO-Validated FTO Recombinant Rabbit Monoclonal Antibody
Description	KD-Validated antibody
Host	Rabbit
Application	WB,FCM,ICC
Reactivity	Human,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	Rabbit IgG
Clonality	Rabbit mAb
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Purification	Affinity purification

Immunogen

Gene Name	FTO
Alternative Names	FTO; FTO Alpha-Ketoglutarate Dependent Dioxygenase; KIAA1752; ALKBH9; U6 Small Nuclear RNA (2'-O-Methyladenosine-N(6)-)-Demethylase FTO; U6 Small Nuclear RNA N(6)-Methyladenosine-Demethylase FTO; MRNA (2'-O-Methyladenosine-N(6)-)-Demethylase FTO; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Intragenic FTO Exon 9 Containing Transcript; MRNA N(6)-Methyladenosine Demethylase FTO; Fat Mass And Obesity-Associated Protein; TRNA N1-Methyl Adenine Demethylase FTO; Fat Mass And Obesity Associated; M6A(M)-Demethylase FTO; AlkB Homolog 9; MGC5149; IFEX9; FTO, Alpha-Ketoglutarate; Dependent Dioxygenase; Alpha-Ketoglutarate-Dependent Dioxygenase; EC 1.14.11.53; EC 1.14.11.-; BMIQ14; GDFD
Gene ID	79068
SwissProt ID	Q9C0B1

Application

Dilution Ratio	WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000
Molecular Weight	Calculated MW: 58.3kDa

Background

This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]

Research Area

Neuroscience,Cardiovascular,Metabolism