KO-Validated YAP1 Recombinant Rabbit Monoclonal Antibody-EnkiLife

KO-Validated YAP1 Recombinant Rabbit Monoclonal Antibody

Summary

Production Name	KO-Validated YAP1 Recombinant Rabbit Monoclonal Antibody
Description	KD-Validated antibody
Host	Rabbit
Application	WB,FCM,ICC
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	Rabbit IgG
Clonality	Rabbit mAb
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Purification	Affinity purification

Immunogen

Gene Name	YAP1
Alternative Names	YAP1; Yes1 Associated Transcriptional Regulator; YAP65; YAP-1; Yes-Associated Protein YAP65 Homolog; Transcriptional Coactivator YAP1; Yes Associated Protein 1; Protein Yorkie Homolog; Yes-Associated Protein 1, 65kDa; 65 KDa Yes-Associated Protein; Yes-Associated Protein 2; Yes-Associated Protein 1; Yorkie Homolog; COB1; YAP2; YAP; YKI
Gene ID	10413
SwissProt ID	P46937

Application

Dilution Ratio	WB 1:2,000-1:10,000; FC 1:200-1:2,000; ICC 1:100-1:1,000
Molecular Weight	Calculated MW: 54.5kDa

Background

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]

Research Area

Signal Transduction,Epigenetics and Nuclear Signaling,Cancer