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MEK1/2 Rabbit Monoclonal antibody

MEK1/2 Rabbit Monoclonal antibody

Cat: AMRe03784
Size:50μL Price:168 $99
Size:100μL Price:300 $180
Application:WB,IHC,ICC/IF,IP
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:MAP2K1/MAP2K2 Category: Recombinant Monoclonal Antibody Tags: , , , , , , , , , ,

Summary

Production Name

MEK1/2 Rabbit Monoclonal antibody

Description

Recombinant rabbit monoclonal antibody

Host

Rabbit

Application

WB,IHC,ICC/IF,IP

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification

Affinity Purified

 

Immunogen

Gene Name

MAP2K1/MAP2K2

Alternative Names

MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1; MAP2K2; MEK2; MKK2; PRKMK2; Dual specificity mitogen-activated protein k

Gene ID

5604/5605

SwissProt ID

Q02750/P36507

 

Application

Dilution Ratio

WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,IP 1:20-1:50

Molecular Weight

Calculated MW: 43,44 kDa; Observed MW: 43,44 kDa

 

Background

Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2.

 

Research Area

Signal Transduction

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