MMP2 (3A8) Mouse Monoclonal Antibody-EnkiLife

MMP2 (3A8) Mouse Monoclonal Antibody

SKU: AMM03859 ★ ★ ★ ★ ★

Size1:50μL Price1:$168
Size2:100μL Price2:$300
Size3:200μL Price3:$520
Application:WB,ICC/IF
Reactivity:Human,Mouse
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:MMP2 Category: Mouse Monoclonal Antibody Tags: Cardiovascular, Mouse, Unconjugated, WB, IF, Human, Mouse

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Summary

Production Name	MMP2 (3A8) Mouse Monoclonal Antibody
Description	Mouse Monoclonal Antibody
Host	Mouse
Application	WB,ICC/IF
Reactivity	Human,Mouse

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG1
Clonality	Monoclonal Antibody
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% sodium azide, pH 7.3.
Purification	Affinity Purification

Immunogen

Gene Name	MMP2
Alternative Names	MMP2; CLG4A; 72 kDa type IV collagenase; 72 kDa gelatinase; Gelatinase A; Matrix metalloproteinase-2; MMP-2; TBE-1
Gene ID	4313
SwissProt ID	P08253

Application

Dilution Ratio	WB: 1:500-1:1000 IF: 1:50-1:200
Molecular Weight	Calculated MW: 74 kDa; Observed MW: 74 kDa

Background

MMP2 Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways.