Maf1 Rabbit Polyclonal Antibody($99/20μL)

Summary

Production Name	Maf1 Rabbit Polyclonal Antibody
Description	Rabbit polyclonal Antibody
Host	Rabbit
Application	IHC,ICC/IF,ELISA
Reactivity	Human,Mouse,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Polyclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% New type preservative N.
Purification	Affinity purification

Immunogen

Gene Name	MAF1
Alternative Names	MAF1; Repressor of RNA polymerase III transcription MAF1 homolog
Gene ID	84232
SwissProt ID	Q9H063

Application

Dilution Ratio	IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:10000-1:20000
Molecular Weight

Background

This gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III). It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression. [provided by RefSeq, Jul 2008],function:Mediator of diverse signals that repress RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.,similarity:Belongs to the MAF1 family.,subunit:Interacts with BRF2.,

Research Area

Epigenetics and Nuclear Signaling; Transcription; Polymerase associated factors; Pol I Transcription; Pol III Transcription; RNA polymerase