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NF-KB p65 Mouse Monoclonal Antibody

NF-KB p65 Mouse Monoclonal Antibody

Cat: AMM85019
Size:50μL Price:$168
Size:100μL Price:$300
Application:WB,IHC,ICC,IP
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:NF-KB p65 Category: Mouse Monoclonal Antibody Tags:

Summary

Production Name

NF-KB p65 Mouse Monoclonal Antibody

Description

Mouse monoclonal Antibody

Host

Mouse

Application

WB,IHC,ICC,IP

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

Mouse IgG1

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.5%protective protein and 50% glycerol.

Purification

Affinity Purification

 

Immunogen

Gene Name

NF-KB p65

Alternative Names

NFKB3; RELA; TF65; Transcription factor p65; p65; NFkB

Gene ID

5970

SwissProt ID

Q04206

 

Application

Dilution Ratio

WB 1:500-1:1000,IHC 1:50-1:100,ICC 1:50-1:200,IP 1:10-1:20

Molecular Weight

Calculated MW: 60 kDa; Observed MW: 65 kDa

 

Background

NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA, or RELB (MIM 604758) to form the NFKB complex. The p50 (NFKB1)/p65 (RELA) heterodimer is the most abundant form of NFKB. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008 or NFKBIB, MIM 604495), which inactivate NFKB by trapping it in the cytoplasm.

 

Research Area

PI3K-Akt signaling pathway,MAPK signaling pathway

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