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NUMB Rabbit Monoclonal Antibody

NUMB Rabbit Monoclonal Antibody

Cat: AMRe83902
Size:50μL Price:$168
Size:100μL Price:$300
Application:WB
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:NUMB Category: Recombinant Monoclonal Antibody Tags:

Summary

Production Name

NUMB Rabbit Monoclonal Antibody

Description

Recombinant rabbit monoclonal antibody

Host

Rabbit

Application

WB

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% protective protein and 50% glycerol.

Purification

Affinity Purification

 

Immunogen

Gene Name

NUMB

Alternative Names

c14_5527; h Numb; Numb; Numb homolog; S171; ;NUMB

Gene ID

SwissProt ID

P49757

 

Application

Dilution Ratio

WB 1:1000-1:2000

Molecular Weight

71 kDa

 

Background

Numb acts as a negative regulator of Notch signaling by promoting ubiquitination and degradation of Notch. The protein is asymmetrically segregated into one daughter cell during cell division, producing two daughter cells with different responses to Notch signaling and different cell fates. The localization of Numb can also be regulated by G-protein coupled receptor (GPCR) and PKC signaling.

 

Research Area

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