PAG Rabbit Monoclonal Antibody

PAG Rabbit Monoclonal Antibody

Cat: AMRe84496
Size:50μL Price:$168
Size:100μL Price:$300
Application:WB,IHC,FC,IP
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:PAG Category: Recombinant Monoclonal Antibody Tags:

Summary

Production Name

PAG Rabbit Monoclonal Antibody

Description

Recombinant rabbit monoclonal antibody

Host

Rabbit

Application

WB,IHC,FC,IP

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% protective protein and 50% glycerol.

Purification

Affinity Purification

 

Immunogen

Gene Name

PAG

Alternative Names

CBP; Csk binding protein; PAG; PAG1;;PAG1

Gene ID

SwissProt ID

Q9NWQ8

 

Application

Dilution Ratio

WB 1:1000-1:2000,IHC 1:100-1:200,FC 1:20-1:100,IP 1:20-1:50

Molecular Weight

Calculated MW: 47 kDa ; Observed MW: 80 kDa

 

Background

Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.

 

Research Area

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