PCGF6 Rabbit Monoclonal Antibody

PCGF6 Rabbit Monoclonal Antibody

Cat: AMRe87596
Size:50μL Price:$168
Size:100μL Price:$300
Application:WB,ICC/IF,IP

Reactivity:Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge).
See other 26 conjugates.

Gene Name:PCGF6
Category: Recombinant Monoclonal Antibody Tags: , , , , , ,

Summary

Production Name

PCGF6 Rabbit Monoclonal Antibody

Description

Recombinant rabbit monoclonal antibody

Host

Rabbit

Application

WB,ICC/IF,IP

Reactivity

Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein. Stable for 12 months from date of receipt.

Purification

Affinity Purification

 

Immunogen

Gene Name

PCGF6

Alternative Names

MBLR; Rnf134; AI604840; 4933407A11Rik

Gene ID

71041

SwissProt ID

Q99NA9

 

Application

Dilution Ratio

WB 1:500-1:2000,ICC/IF 1:100-1:200,IP 1:20-1:50

Molecular Weight

Calculated MW:40 kDa; Observed MW:40 kDa

 

Background

Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity.

 

Research Area

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