Summary
Performance
Immunogen
Application
Background
protein kinase (cAMP-dependent, catalytic) inhibitor beta(PKIB) Homo sapiens This gene encodes a member of the cAMP-dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012],function:Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.,similarity:Belongs to the PKI family.,
Research Area
Protein Phosphorylation; Ser / Thr Kinases; PKA; Cancer; Signal transduction; Protein phosphorylation; Serine/threonine kinases
