Summary
Performance
Immunogen
Application
Background
The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011],lipid transport, response to organic substance, lipid localization, response to organic cyclic substance, monocarboxylic acid transport, organic acid transport, fatty acid transport, long-chain fatty acid transport, lipid storage, response to drug, carboxylic acid transport,
Research Area
Cancer; Metabolism; Types of disease; Heart disease; Pathways and Processes; Metabolism processes; Hypoxia; Metabolic signaling pathways; Lipid and lipoprotein metabolism; Lipid metabolism; Metabolism of lipids and lipoproteins; Cardiovascular; Hypoxia; Hypoxia-Regulated; Lipids / Lipoproteins; Adipose Related; Lipid Droplet Protein; Signal Transduction; Lipid metabolism; Atherosclerosis; Lipid transport; Cancer Metabolism; Metabolism of lipids and lipoproteins
