PMEL17 / GP100 (2Z15) Rabbit Monoclonal Antibody

PMEL17 / GP100 (2Z15) Rabbit Monoclonal Antibody

SKU: AMRe16301 ★ ★ ★ ★ ★
Size1:50μL Price1:$128
Size2:100μL Price2:$230
Size3:200μL Price3:$380
Application:WB,IHC-P,ICC/IF,FC,IP,IF-P
Reactivity:Human,Mouse
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:PMEL Category: Recombinant Monoclonal Antibody Tags: , , , , , , , , ,

Summary

Production Name

PMEL17 / GP100 (2Z15) Rabbit Monoclonal Antibody

Description

Rabbit Monoclonal Antibody

Host

Rabbit

Application

WB,IHC-P,ICC/IF,FC,IP,IF-P

Reactivity

Human,Mouse

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Purification

Affinity purification

 

Immunogen

Gene Name

PMEL

Alternative Names

PMEL; ME20-M; Premelanosome protein; Silver locus protein homolog; PMEL17; SILV;

Gene ID

6490

SwissProt ID

P40967

 

Application

Dilution Ratio

WB 1:1000-1:5000, IHC-P/IF-P 1:100-1:500, ICC/IF 1:50, FC 1:200-1:500, IP 1:20-1:50

Molecular Weight

70kDa

 

Background

Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity. Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.

 

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