Summary
Performance
Immunogen
Application
Background
E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome.
Research Area
Apoptosis,PI3K-Akt signaling pathway
Summary
| Production Name | Phospho-MDM2 (Ser166) Rabbit Monoclonal Antibody |
| Description | Recombinant rabbit monoclonal antibody |
| Host | Rabbit |
| Application | WB,IHC |
| Reactivity | Human,Rat |
Performance
| Conjugation | Unconjugated |
| Modification | Phosphorylated |
| Isotype | IgG |
| Clonality | Monoclonal |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | Purified antibody in TBS with 0.05% sodium azide,0.05%protective protein and 50% glycerol. |
| Purification | Affinity Purification |
Immunogen
| Gene Name | Phospho-MDM2 (Ser166) |
| Alternative Names | Double minute 2 protein; Hdm2; Oncoprotein Mdm2 |
| Gene ID | 4193 |
| SwissProt ID | Q00987 |
Application
| Dilution Ratio | WB 1:500-1:1000,IHC 1:50-1:100 |
| Molecular Weight | Calculated MW: 55 kDa; Observed MW: 90 kDa |
Background
E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome.
Research Area
Apoptosis,PI3K-Akt signaling pathway
