Name: Phospho-PKR (Thr446) Rabbit Polyclonal Antibody
Brand: Enkilife Limited
SKU: APRab00921
Price: 99 USD
Availability: InStock

Phospho-PKR (Thr446) Rabbit Polyclonal Antibody($99/20μL)

Cat: APRab00921

Size:20μL Price:$99
Size:50μL Price:$150
Size:100μL Price:$280
Size:200μL Price:$520
Application:WB
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:EIF2AK2 Category: Polyclonal Antibodies Tags: Phospho, Signal Transduction, Rabbit, WB, Human

Datasheet

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Summary

Production Name	Phospho-PKR (Thr446) Rabbit Polyclonal Antibody
Description	Rabbit polyclonal Antibody
Host	Rabbit
Application	WB
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Phosphorylated
Isotype	IgG
Clonality	Polyclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% sodium azide, pH 7.3.
Purification	Affinity Purification

Immunogen

Gene Name	EIF2AK2
Alternative Names	EIF2AK2; PKR; PRKR; Interferon-induced; double-stranded RNA-activated protein kinase; Eukaryotic translation initiation factor 2-alpha kinase 2; eIF-2A protein kinase 2; Interferon-inducible RNA-dependent protein kinase; P1/eIF-2A protein k
Gene ID	5610
SwissProt ID	P19525

Application

Dilution Ratio	WB 1:500-1:1000
Molecular Weight	Calculated MW: 62 kDa; Observed MW: 68 kDa

Background

PKR a protein kinase of the PEK family. Upon binding double-stranded RNA, it becomes autophosphorylated and activated. Phosphorylates and inhibits the alpha subunit of eIF2 alpha, which leads to an inhibition of the initiation of protein synthesis.

Research Area

Signal Transduction