Name: Phospho-PML Protein (Ser518) Rabbit Monoclonal Antibody
Brand: Enkilife Limited
SKU: AMRe84914
Price: 168 USD
Availability: InStock
Rating: 5 (1 reviews)

Phospho-PML Protein (Ser518) Rabbit Monoclonal Antibody

Cat: AMRe84914

Size:50μL Price:$168
Size:100μL Price:$300
Application:WB,IHC
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:Phospho-PML Protein (Ser518) Category: Recombinant Monoclonal Antibody Tags: Apoptosis, mTOR signaling pathway, Rabbit, Unconjugated, WB, IHC, Human

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Summary

Production Name	Phospho-PML Protein (Ser518) Rabbit Monoclonal Antibody
Description	Recombinant rabbit monoclonal antibody
Host	Rabbit
Application	WB,IHC
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Phosphorylated
Isotype	IgG
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Purified antibody in TBS with 0.05% sodium azide,0.05%protective protein and 50% glycerol.
Purification	Affinity Purification

Immunogen

Gene Name	Phospho-PML Protein (Ser518)
Alternative Names	PML; MYL; RNF71; TRIM19; Protein PML; Promyelocytic leukemia protein; RING finger protein 71; Tripartite motif-containing protein 19
Gene ID	5371
SwissProt ID	P29590

Application

Dilution Ratio	WB 1:500-1:1000,IHC 1:50-1:100
Molecular Weight	Calculated MW: 98 kDa; Observed MW: 98,117 kDa

Background

Regulates RB1 phosphorylation and activity. Required for normal development of the brain cortex during embryogenesis. Can sequester herpes virus and varicella virus proteins inside PML bodies, and thereby inhibit the formation of infectious viral particles. Regulates phosphorylation of ITPR3 and plays a role in the regulation of calcium homeostasis at the endoplasmic reticulum (By similarity). Regulates transcription activity of ELF4.

Research Area

Apoptosis,mTOR signaling pathway