Phospho-PP2A alpha(Y307) Rabbit Monoclonal Antibody

Phospho-PP2A alpha(Y307) Rabbit Monoclonal Antibody

Cat: AMRe83690
Size:50μL Price:$168
Size:100μL Price:$300
Application:WB,IHC,ICC/IF,ICC,IP
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:Phospho-PP2A alpha(Y307) Category: Recombinant Monoclonal Antibody Tags:

Summary

Production Name

Phospho-PP2A alpha(Y307) Rabbit Monoclonal Antibody

Description

Recombinant rabbit monoclonal antibody

Host

Rabbit

Application

WB,IHC,ICC/IF,ICC,IP

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Phosphorylated

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% protective protein and 50% glycerol.

Purification

Affinity Purification

 

Immunogen

Gene Name

Phospho-PP2A alpha(Y307)

Alternative Names

eplication protein C; PP2A-alpha; Replication protein C; RP-C; PPP2CA; MGC786;p-PP2A alpha (Y307)

Gene ID

SwissProt ID

P67775

 

Application

Dilution Ratio

WB 1:1000-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200,IP 1:20-1:50

Molecular Weight

Calculated MW: 36 kDa ; Observed MW: 35 kDa

 

Background

PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.

 

Research Area

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