Name: PinX1 Rabbit Polyclonal Antibody
Brand: Enkilife Limited
SKU: APRab16159
Price: 118 USD
Availability: InStock
Rating: 5 (1 reviews)

PinX1 Rabbit Polyclonal Antibody($99/20μL)

Cat: APRab16159

Size:20μL Price:$99
Size:50μL Price:$118
Size:100μL Price:$220
Size:200μL Price:$380
Application:IHC,ICC/IF,ELISA
Reactivity:Human,Rat,Mouse
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:PINX1 Category: Polyclonal Antibody Tags: Epigenetics and Nuclear Signaling, DNA / RNA, DNA Synthesis, Topoisomerases

Datasheet

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Summary

Production Name	PinX1 Rabbit Polyclonal Antibody
Description	Rabbit polyclonal Antibody
Host	Rabbit
Application	IHC,ICC/IF,ELISA
Reactivity	Human,Rat,Mouse

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Polyclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% New type preservative N.
Purification	Affinity purification

Immunogen

Gene Name	PINX1
Alternative Names	PINX1; LPTL; LPTS; PIN2/TERF1-interacting telomerase inhibitor 1; Liver-related putative tumor suppressor; Pin2-interacting protein X1; Protein 67-11-3; TRF1-interacting protein 1
Gene ID	54984
SwissProt ID	Q96BK5

Application

Dilution Ratio	IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:10000-1:20000
Molecular Weight

Background

domain:The TID (telomerase inhibiting domain) domain is sufficient to bind TERT and inhibit its activity.,function:Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor.,similarity:Belongs to the PINX1 family.,similarity:Contains 1 G-patch domain.,subcellular location:In nucleoli and at telomere speckles.,subunit:Binds to MCRS1, TERT and TERF1.,tissue specificity:Ubiquitous; expressed at low levels. Not detectable in a number of hepatocarcinoma cell lines.,domain:The TID (telomerase inhibiting domain) domain is sufficient to bind TERT and inhibit its activity.,function:Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor.,similarity:Belongs to the PINX1 family.,similarity:Contains 1 G-patch domain.,subcellular location:In nucleoli and at telomere speckles.,subunit:Binds to MCRS1, TERT and TERF1.,tissue specificity:Ubiquitous; expressed at low levels. Not detectable in a number of hepatocarcinoma cell lines.,

Research Area

Epigenetics and Nuclear Signaling; DNA / RNA; DNA Synthesis; Topoisomerases